Carpachromene
Carpachromene is a potent α-glucosidase enzyme inhibitor. Carpachromene ameliorates insulin resistance in HepG2 cells via modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 pathway[1].
Product Specifications
CAS Number
[57498-96-1]
UNSPSC
12352005
Hazard Statement
H410
Target
Glycosidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carpachromene.html
Purity
98.84
Solubility
10 mM in DMSO
Smiles
OC1=C2C(OC(C3=CC=C(O)C=C3)=CC2=O)=CC4=C1C=CC(C)(C)O4
Molecular Formula
C20H16O5
Molecular Weight
336.34
Precautions
H410
References & Citations
[1]Alaaeldin R, et al. Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway. Molecules. 2021 Dec 16;26 (24) :7629.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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