3-epi-Isocucurbitacin B
3-epi-Isocucurbitacin B (Compound 5) is a cucurbitane triterpene derived from Trichosanthes kirilowii. 3-epi-Isocucurbitacin B shows significant cytotoxicity to human tumor cells A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT15[1].
Product Specifications
CAS Number
[89647-62-1]
UNSPSC
12352211
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-epi-isocucurbitacin-b.html
Solubility
10 mM in DMSO
Smiles
C[C@@]([C@@](CC=C(C(C)([C@H]1O)C)[C@@]2([H])CC1=O)([H])[C@@]32C)(C[C@H]4O)[C@@]([C@@]4([H])[C@@](C)(O)C(/C=C/C(C)(C)OC(C)=O)=O)(CC3=O)C
Molecular Formula
C32H46O8
Molecular Weight
558.70
References & Citations
[1]Shi Yong Ryu, et al. Antitumor activity of Trichosanthes kirilowii. 1994;17 (5) :348–353.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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