AGO3 Protein

<strong>AGO3 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2016704_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 100.4 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Argonaute 3, RISC Catalytic Component, Eukaryotic Translation Factor 2C, EIF2C3, HAgo3, Argonaute3, EIF-2C, EIF2C_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Brennecke J, Aravin AA, Stark A, Dus M, Kellis M, Sachidanandam R, Hannon GJ. Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila Cell. 2007 Mar 23;128(6):1089-103._x000D_ 2: Park MS, Phan HD, Busch F, Hinckley SH, Brackbill JA, Wysocki VH, Nakanishi K. Human Argonaute3 has slicer activity Nucleic Acids Res. 2017 Nov 16;45(20):11867-11877._x000D_ 3: Friend K, Campbell ZT, Cooke A, Kroll-Conner P, Wickens MP, Kimble J. A conserved PUF-Ago-eEF1A complex attenuates translation elongation Nat Struct Mol Biol. 2012 Jan 8;19(2):176-83._x000D_ 4: Qi HH, Ongusaha PP, Myllyharju J, Cheng D, Pakkanen O, Shi Y, Lee SW, Peng J, Shi Y. Prolyl 4-hydroxylation regulates Argonaute 2 stability Nature. 2008 Sep 18;455(7211):421-4._x000D_ 5: Gunawardane LS, Saito K, Nishida KM, Miyoshi K, Kawamura Y, Nagami T, Siomi H, Siomi MC. A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila Science. 2007 Mar 16;315(5818):1587-90._x000D_ 6: Jakymiw A, Ikeda K, Fritzler MJ, Reeves WH, Satoh M, Chan EK. Autoimmune targeting of key components of RNA interference Arthritis Res Ther. 2006;8(4):R87._x000D_ 7: Turchinovich A, Surowy HM, Tonevitsky AG, Burwinkel B. Interference in transcription of overexpressed genes by promoter-proximal downstream sequences Sci Rep. 2016 Aug 3;6:30735._x000D_ 8: Schürmann N, Trabuco LG, Bender C, Russell RB, Grimm D. Molecular dissection of human Argonaute proteins by DNA shuffling Nat Struct Mol Biol. 2013 Jul;20(7):818-26._x000D_ 9: Hauptmann J, Dueck A, Harlander S, Pfaff J, Merkl R, Meister G. Turning catalytically inactive human Argonaute proteins into active slicer enzymes Nat Struct Mol Biol. 2013 Jul;20(7):814-7._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/22916019">10: van Mierlo JT, Bronkhorst AW, Overheul GJ, Sadanandan SA, Ekström JO, Heestermans M, Hultmark D, Antoniewski C, van Rij RP. Convergent evolution of argonaute-2 slicer antagonism in two distinct insect RNA viruses PLoS Pathog. 2012;8(8):e1002872. </a>_x000D_ _x000D_ <strong>Products Related to AGO3 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>