Pipemidic acid (trihydrate)

Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections[1][2].

Product Specifications

CAS Number

[72571-82-5]

UNSPSC

12352200

Hazard Statement

H317, H334

Target

Antibiotic; Bacterial

Type

Biochemical Assay Reagents

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/pipemidic-acid-trihydrate.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

CCN1C=C(C(O)=O)C(C2=CN=C(N3CCNCC3)N=C21)=O.O.O.O

Molecular Formula

C14H23N5O6

Molecular Weight

357.36

Precautions

H317, H334

References & Citations

[1]Iacovino R, et al. β-Cyclodextrin inclusion complex to improve physicochemical properties of pipemidic acid: characterization and bioactivity evaluation. Int J Mol Sci. 2013 Jun 25;14 (7) :13022-41.|[2]Aoyama H, et, al. Purification of Citrobacter freundii DNA gyrase and inhibition by quinolones. Antimicrob Agents Chemother. 1988 Jan;32 (1) :104-9. |[3]Shimizu M, et, al. Pipemidic acid: absorption, distribution, and excretion. Antimicrob Agents Chemother. 1975 Apr;7 (4) :441-6.