eIF4A2 Recombinant Rabbit Monoclonal Antibody [PSH01-88]
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
Eukaryotic initiation factor 4A-II eIF-4A-II; eIF4A-II ATP-dependent RNA helicase eIF4A-2 EIF4A2 DDX2B, EIF4F
Swiss Prot
Q14240 Human,Q5RKI1 Rat,P10630 Mouse
Cellular Locus
Cytosol.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat,Monkey
Immunogen
Recombinant protein within Human eIF4A2 aa1-407.
Isotype
IgG
Clone
PSH01-88
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:1,000 ;IF-Cell: 1:100 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 46 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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