E3 ligase Ligand 28
TRIM7-IN-1 (compound89) is a potent TRIM7 inhibitor with a KD value of 2.6 µM[1].
Product Specifications
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-28.html
Smiles
NC(CC[C@H](NC([C@@H](N1CC2=C(C1=O)C=C(C=C2)Br)CC3=CC=CC=C3)=O)C(O)=O)=O
Molecular Formula
C22H22BrN3O5
Molecular Weight
488.33
References & Citations
[1]Muñoz Sosa CJ, et al. A C-Degron Structure-Based Approach for the Development of Ligands Targeting the E3 Ligase TRIM7. ACS Chem Biol. 2024 Jul 19;19 (7) :1638-1647.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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