Galangin-13C3

Galangin-13C3 is the 13C-labeled Galangin. Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor. Galangin (Norizalpinin) also shows inhibition of CYP1A1 activity.

Product Specifications

UNSPSC

12352005

Target

Autophagy; Cytochrome P450; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Autophagy; Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/galangin-13c3.html

Solubility

10 mM in DMSO

Smiles

O=[13C]1[13C](O)=[13C](C2=CC=CC=C2)OC3=CC(O)=CC(O)=C13

Molecular Formula

C12 13C3H10O5

Molecular Weight

273.21

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Ciolino HP, et al. The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor. Br J Cancer. 1999 Mar;79 (9-10) :1340-6.|[3]Wen M, et al. Galangin induces autophagy through upregulation of p53 in HepG2 cells. Pharmacology. 2012;89 (5-6) :247-55.