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ROCK2-IN-2

ROCK2-IN-2 is a selective ROCK2 inhibitor extracted from patent US20180093978A1, Compound A-30, has an IC50 of <1 μM.

Product Specifications

CAS Number

1995065-79-6

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

ROCK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ROCK2-IN-2.html

Concentration

10mM

Purity

98.05

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C12=CC(NC3=NN=C(C4=CC(C5=NC=CO5)=CC=C4)S3)=CC=C1NN=C2

Molecular Formula

C18H12N6OS

Molecular Weight

360.39

Precautions

H315, H319, H320

References & Citations

[1]Aicher, Thomas Daniel, et al. INDAZOLYL THIADIAZOLAMINES AND RELATED COMPOUNDS FOR INHIBITION OF RHO-ASSOCIATED PROTEIN KINASE AND THE TREATMENT OF DISEASE. US20180093978A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ROCK2

Available Sizes

Frequently Asked Questions

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