ROCK2-IN-2
ROCK2-IN-2 is a selective ROCK2 inhibitor extracted from patent US20180093978A1, Compound A-30, has an IC50 of <1 μM.
Product Specifications
CAS Number
[1995065-79-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ROCK2-IN-2.html
Concentration
10mM
Purity
98.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C12=CC(NC3=NN=C(C4=CC(C5=NC=CO5)=CC=C4)S3)=CC=C1NN=C2
Molecular Formula
C18H12N6OS
Molecular Weight
360.39
Precautions
H315, H319, H320
References & Citations
[1]Aicher, Thomas Daniel, et al. INDAZOLYL THIADIAZOLAMINES AND RELATED COMPOUNDS FOR INHIBITION OF RHO-ASSOCIATED PROTEIN KINASE AND THE TREATMENT OF DISEASE. US20180093978A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ROCK2
Available Sizes
Curated Selection
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