Clotrimazole

Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity.

Product Specifications

CAS Number

[23593-75-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H410

Target

Antibiotic; Autophagy; Bacterial; Fungal

Type

Reference compound

Related Pathways

Anti-infection; Autophagy

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/Clotrimazole.html

Purity

99.91

Solubility

DMSO : 33.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

ClC1=CC=CC=C1C(N2C=CN=C2)(C3=CC=CC=C3)C4=CC=CC=C4

Molecular Formula

C22H17ClN2

Molecular Weight

344.84

Precautions

H302, H315, H319, H410

References & Citations

[1]Sawyer PR, Clotrimazole: a review of its antifungal activity and therapeutic efficacy. Drugs. 1975;9 (6) :424-47.|[2]Witzke A, Inhibition of the gastric H, K-ATPase by clotrimazole. Biochemistry. 2010 Jun 1;49 (21) :4524-32.|[3]Schaller K. In vitro antibacterial activity of different clotrimazole formulations. Chemotherapy. 1982;28 Suppl 1:32-6.