DMT-dG (ib) Phosphoramidite-15N5

DMT-dG (ib) Phosphoramidite-15N5 is the 15N labeled DMT-dG (ib) Phosphoramidite (HY-W008848) . DMT-dG (ib) Phosphoramidite is a phosphoramidite monomer that can be used in the synthesis of DNA and related molecules[1][2].

Product Specifications

UNSPSC

12352005

Target

DNA/RNA Synthesis; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Others

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dmt-dg-ib-phosphoramidite-15n5.html

Solubility

10 mM in DMSO

Smiles

CC(N(P(OC1C[C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)C4=CC=C(C=C4)OC)[15N]5C([15N]=C([15NH]6)[15NH]C(C(C)C)=O)=C([15N]=CC5)C6=O)OCCC#N)C(C)C)C

Molecular Formula

C45H56N2 15N5O8P

Molecular Weight

858.91

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]James D Thorpe, et al. Mechanochemical Synthesis of Short DNA Fragments. Chemistry. 2020 Jul 22;26 (41) :8857-8861.