m-PEG10-acid
Product Specifications
UNSPSC Description
m-PEG10-acid is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG10-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
Target Antigen
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m-peg10-acid.html
Solubility
10 mM in DMSO
Smiles
OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O
Molecular Weight
500.58
References & Citations
[1]John F. Donovan et al. Pegylated prodrugs of phenolic trpv1 agonists. WO2020023794A1.|[2]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140500/m-PEG10-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140500/m-PEG10-acid-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2409969-94-2
Available Sizes
Curated Selection
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