STING18
STING18 (Stimulator of interferon genes 18) is a compound that inhibits STING protein by utilizing a small molecule active site dimer, with good oral exposure, slow binding kinetics, and functional inhibitory activity on STING-mediated cytokine release.
Product Specifications
CAS Number
[2706536-26-5]
Product Name Alternative
Stimulator of interferon genes 18
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sting18.html
Purity
98.60
Solubility
DMF : 10 mg/mL (ultrasonic; warming)
Smiles
O=C(CC1C2=CC=C(C=C2C(N(C1C3=CC=C4OCCOC4=C3)C5=CC=C(C(C)(C)C)C(Cl)=C5)=O)F)O
Molecular Formula
C29H27ClFNO5
Molecular Weight
523.98
References & Citations
[1]Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
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