STING18

STING18 (Stimulator of interferon genes 18) is a compound that inhibits STING protein by utilizing a small molecule active site dimer, with good oral exposure, slow binding kinetics, and functional inhibitory activity on STING-mediated cytokine release.

Product Specifications

CAS Number

[2706536-26-5]

Product Name Alternative

Stimulator of interferon genes 18

UNSPSC

12352005

Target

STING

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sting18.html

Purity

98.60

Solubility

DMF : 10 mg/mL (ultrasonic; warming)

Smiles

O=C(CC1C2=CC=C(C=C2C(N(C1C3=CC=C4OCCOC4=C3)C5=CC=C(C(C)(C)C)C(Cl)=C5)=O)F)O

Molecular Formula

C29H27ClFNO5

Molecular Weight

523.98

References & Citations

[1]Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Curated Selection

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