EEDi-5285

EEDi-5285 is an exceptionally potent and orally active embryonic ectoderm development (EED) inhibitor with an IC50 value of 0.2 nM for binds to the EED protein. EEDi-5285 has anti-cancer activity[1].

Product Specifications

CAS Number

[2488952-40-3]

UNSPSC

12352005

Target

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/eedi-5285.html

Purity

99.87

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

CS(C1=C2C(C3=CC=C(C4CC4)N=C3)=CN=C(NCC5=C(F)C=CC6=C5CCO6)N2C=N1)(=O)=O

Molecular Formula

C24H22FN5O3S

Molecular Weight

479.53

References & Citations

[1]Rohan Kalyan Rej, et al. EEDi-5285: An Exceptionally Potent, Efficacious, and Orally Active Small-Molecule Inhibitor of Embryonic Ectoderm Development. J Med Chem. 2020 Jul 9;63 (13) :7252-7267.