18-HETE

18-HETE (compound 3) is a monooxygenase metabolite of cytochrome P450 (CYP450) .18- HETE consists of arachidonic acid bearing a hydroxy substituent at position 18[1].

Product Specifications

CAS Number

[133268-58-3]

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/18-hete.html

Solubility

10 mM in DMSO

Smiles

CCC(O)CC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O

Molecular Formula

C20H32O3

Molecular Weight

320.47

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Bertrand Heckmann; et al. Chiral acetals: Stereocontrolled syntheses of 16-, 17-, and 18-hydroxyeicosatetraenoic acids, cytochrome P-450 arachidonate metabolites.Tetrahedron Letters ,1996, 37 (9), 1425-1428.