Desoxo-narchinol A

Desoxo-narchinol A is an orally active and potent anti-inflammatory agent. Desoxo-narchinol A can be isolated from the roots and rhizomes of Nardostachys jatamansi. Desoxo-narchinol A can be used for septic shock and inflammatory diseases research[1][2][3].

Product Specifications

CAS Number

[53859-06-6]

UNSPSC

12352211

Target

COX; NO Synthase; PGE synthase; TNF Receptor

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/desoxo-narchinol-a.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

C[C@@]1([C@@H](C=C2)O)C(C2=O)=CCC[C@H]1C

Molecular Formula

C12H16O2

Molecular Weight

192.25

References & Citations

[1]Itokawa H, et al. Cytotoxic sesquiterpenes from Nardostachys chinensis. Chem Pharm Bull (Tokyo) . 1993 Jun;41 (6) :1183-4.|[2]Shin JY, et al. Anti-inflammatory effect of desoxo-narchinol-A isolated from Nardostachys jatamansi against lipopolysaccharide. Int Immunopharmacol. 2015 Dec;29 (2) :730-738. |[3]Thapa SK, Upadhyay M, Kim TH, Shin S, Park SJ, Shin BS. Liquid Chromatography-Tandem Mass Spectrometry of Desoxo-Narchinol a and Its Pharmacokinetics and Oral Bioavailability in Rats and Mice. Molecules. 2019 May 28;24 (11) :2037.