MDI-2268
MDI-2268 is an inhibitor of plasma kallikrein inhibitor 1 (PAI-1) . MDI-2268 has good antithrombotic properties and regulates blood coagulation and fibrinolysis process by enhancing fibrinolysis. MDI-2268 can be used in research areas such as deep vein thrombosis[1].
Product Specifications
CAS Number
[1609176-50-2]
UNSPSC
12352005
Target
Apoptosis; PAI-1
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/mdi-2268.html
Concentration
10mM
Purity
99.73
Solubility
DMSO : 166.67 mg/mL (ultrasonic)
Smiles
O=C(NN)C(NCC1=CC=CC(OC(F)(F)F)=C1)=O
Molecular Formula
C10H10F3N3O3
Molecular Weight
277.20
References & Citations
[1]Gordon A, et al. Natural History of Stasis-Induced Deep Venous Thrombosis in a Murine Model and Application in the Clinical Setting: A Histochemical Approach[J]. Journal of Vascular Surgery: Venous and Lymphatic Disorders, 2020, 8 (2) : 309.|[2]Sun S, et al., Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction. Sci Immunol. 2024 Nov 8;9 (101) :eadi7907.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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