Clodronic acid

Clodronic acid is an orally active bisphosphonate, which is used for researching osteoporosis and diseases associated with excessive bone resorption. Clodronic acid inhibits bone resorption through induction of osteoclast apoptosis. Clodronic acid is effective in the maintenance or improvement of bone mineral density[1].

Product Specifications

CAS Number

[10596-23-3]

Product Name Alternative

Clodronate

UNSPSC

12352211

Hazard Statement

H290, H314

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others; Cancer

Assay Protocol

https://www.medchemexpress.com/clodronic-acid.html

Purity

99.41

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

ClC(P(O)(O)=O)(Cl)P(O)(O)=O

Molecular Formula

CH4Cl2O6P2

Molecular Weight

244.89

Precautions

H290, H314

References & Citations

[1]Frediani B, et al. Clodronic acid formulations available in Europe and their use in osteoporosis: a review. Clin Drug Investig. 2009;29 (6) :359-79.