FA-PEG5-Mal
FA-PEG5-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
Product Name Alternative
Folic acid-PEG5-Mal
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fa-peg5-mal.html
Purity
99.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N=C(N1)N)N=CC(CNC3=CC=C(C=C3)C(N[C@@H](CCC(NCCOCCOCCOCCOCCOCCN4C(C=CC4=O)=O)=O)C(O)=O)=O)=N2
Molecular Formula
C35H45N9O12
Molecular Weight
783.78
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
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