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FA-PEG5-Mal

FA-PEG5-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

Product Name Alternative

Folic acid-PEG5-Mal

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fa-peg5-mal.html

Purity

99.46

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C2=C(N=C(N1)N)N=CC(CNC3=CC=C(C=C3)C(N[C@@H](CCC(NCCOCCOCCOCCOCCOCCN4C(C=CC4=O)=O)=O)C(O)=O)=O)=N2

Molecular Formula

C35H45N9O12

Molecular Weight

783.78

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Frequently Asked Questions

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