(R)-MG-132
Product Specifications
Product Name Alternative
(S,R,S)-(-)-MG-132; Z-Leu-D-Leu-Leu-al
UNSPSC Description
(R)-MG-132 ((S,R,S)-(-)-MG-132) is the enantiomer of MG-132. (R)-MG-132 is a proteasome inhibitor with weaker cell cytotoxicity than MG-132[1].
Target Antigen
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-mg-132.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@H](CC(C)C)C(N[C@@H](CC(C)C)C=O)=O)[C@H](CC(C)C)NC(OCC1=CC=CC=C1)=O
Molecular Weight
475.62
References & Citations
[1]Mroczkiewicz M, et al. Studies of the synthesis of all stereoisomers of MG-132 proteasome inhibitors in the tumor targeting approach. J Med Chem. 2010 Feb 25;53(4):1509-18.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-13259C/R-MG-132-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13259C/R-MG-132-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1211877-36-9
Available Sizes
Curated Selection
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