(R) -MG-132
(R) -MG-132 ((S, R, S) - (-) -MG-132) is the enantiomer of MG-132. (R) -MG-132 is a proteasome inhibitor with weaker cell cytotoxicity than MG-132[1].
Product Specifications
CAS Number
[1211877-36-9]
Product Name Alternative
(S, R, S) - (-) -MG-132; Z-Leu-D-Leu-Leu-al
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-mg-132.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@H](CC(C)C)C(N[C@@H](CC(C)C)C=O)=O)[C@H](CC(C)C)NC(OCC1=CC=CC=C1)=O
Molecular Formula
C26H41N3O5
Molecular Weight
475.62
Precautions
H302, H315, H319, H335
References & Citations
[1]Mroczkiewicz M, et al. Studies of the synthesis of all stereoisomers of MG-132 proteasome inhibitors in the tumor targeting approach. J Med Chem. 2010 Feb 25;53 (4) :1509-18.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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