MBL-IN-3
MBL-IN-3 (compound 72922413) is a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor (IC50=54±4 μM). MBL-IN-3 is identified and shown to lower minimum inhibitory concentrations (MICs) of Meropenem for a panel of E. coli and K. pneumoniae clinical isolates expressing NDM-1. MBL-IN-3 can be used for antibiotic sensitizer research[1].
Product Specifications
CAS Number
1452395-68-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mbl-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C(N(CC2)CCC32C(O)CCCO3)=O)=CN=C4N1C=CC=C4O
Molecular Formula
C18H21N3O5
Molecular Weight
359.38
References & Citations
[1]Cheng Z, et al. Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase[J]. Journal of Chemical Information and Modeling, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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