Recombinant DNMT1 Protein

<strong>Recombinant DNMT1 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017216_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 20 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 188.2 kDa_x000D_ <strong>Supplied as:</strong> Gel_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> AIM, DNMT, MCMT, CXXC9, HSN1E, ADCADN_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Weinberg DN, Papillon-Cavanagh S, Chen H, Yue Y, Chen X, Rajagopalan KN, Horth C, McGuire JT, Xu X, Nikbakht H, Lemiesz AE, Marchione DM, Marunde MR, Meiners MJ, Cheek MA, Keogh MC, Bareke E, Djedid A, Harutyunyan AS, Jabado N, Garcia BA, Li H, Allis CD, Majewski J, Lu C. The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape Nature. 2019 Sep;573(7773):281-286._x000D_ 2: Wei Y, Lao XM, Xiao X, Wang XY, Wu ZJ, Zeng QH, Wu CY, Wu RQ, Chen ZX, Zheng L, Li B, Kuang DM. Plasma Cell Polarization to the Immunoglobulin G Phenotype in Hepatocellular Carcinomas Involves Epigenetic Alterations and Promotes Hepatoma Progression in Mice Gastroenterology. 2019 May;156(6):1890-1904.e16._x000D_ 3: Du Q, Wang Z, Schramm VL. Human DNMT1 transition state structure Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):2916-21._x000D_ 4: Zhu B, Chen JJ, Feng Y, Yang JL, Huang H, Chung WY, Hu YL, Xue WJ. DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma J Exp Clin Cancer Res. 2021 Nov 8;40(1):352._x000D_ 5: Xiang S, Zou P, Tang Q, Zheng F, Wu J, Chen Z, Hann SS. HOTAIR-mediated reciprocal regulation of EZH2 and DNMT1 contribute to polyphyllin I-inhibited growth of castration-resistant prostate cancer cells in vitro and in vivo Biochim Biophys Acta Gen Subj. 2018 Mar;1862(3):589-599._x000D_ 6: Tsung AJ, Guda MR, Asuthkar S, Labak CM, Purvis IJ, Lu Y, Jain N, Bach SE, Prasad DVR, Velpula KK. Methylation regulates HEY1 expression in glioblastoma Oncotarget. 2017 Jul 4;8(27):44398-44409._x000D_ 7: Lee B, Morano A, Porcellini A, Muller MT. GADD45α inhibition of DNMT1 dependent DNA methylation during homology directed DNA repair Nucleic Acids Res. 2012 Mar;40(6):2481-93._x000D_ 8: Lavoie G, Estève PO, Laulan NB, Pradhan S, St-Pierre Y. PKC isoforms interact with and phosphorylate DNMT1 BMC Biol. 2011 May 27;9:31._x000D_ 9: Ma Y, Ma J, Zhang X, Chen W, Yu L, Lu Y, Bai L, Shen B, Huang X, Zhang L. Generation of eGFP and Cre knockin rats by CRISPR/Cas9 FEBS J. 2014 Sep;281(17):3779-90._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/36482819">10: Gan W, Kang Y, Wu Y, Zhu J, Chen Y, Kuang J, Li J, Yang L. Hepatitis B virus X protein induces p16 gene promoter methylation through upregulation of DNA methylation transferases DNMT1 and DNMT3A Adv Clin Exp Med. 2023 May;32(5):583-592. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant DNMT1 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>