Human CD45RO Protein, His Tag (MALS verified)
Human CD45RO Protein, His Tag (CDO-H52H3) is expressed from human 293 cells (HEK293) . It contains AA Gln 26 - Lys 416 (Accession # P08575-4) .
Product Specifications
Background
CD45RO contains exon 3,7 and 8 and lacks the RA, RB and RC exons of the CD45 gene. CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.4 kDa. The protein migrates as 70-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P08575-4
Expression Region
Gln 26 - Lys 416
Host
HEK293
Target
CD45RO
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
46.4 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CDO-H52H3.pdf
Species
Human
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