2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid

2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid, a natural ursane-type triterpene, is a potent inhibitor of HIV protease (HIV Protease) . 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid is also an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA) . 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid displays an inhibitory activity against nitric oxide production in Lipopolysaccharide (Lipopolysaccharides) -activated RAW 264.7 cells[1][2].

Product Specifications

CAS Number

[176983-21-4]

UNSPSC

12352211

Target

EBV; HIV Protease; HSV

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/2α-19α-dihydroxy-3-oxo-urs-12-en-28-oic-acid.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

OC([C@]12[C@]([C@](O)([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)(C([C@@H](C4)O)=O)C)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O

Molecular Formula

C30H46O5

Molecular Weight

486.68

References & Citations

[1]Xiao-Peng Wu, et al. A new ursane-type triterpene, cymosic acid from Rosa cymosa. J Asian Nat Prod Res. 2014;16 (4) :422-5. |[2]Shoko Taniguchi, et al. Production of bioactive triterpenes by Eriobotrya japonica calli. Phytochemistry. 2002 Feb;59 (3) :315-23. |[3]Xiao-Peng Wu, et al. A new ursane-type triterpene, cymosic acid from Rosa cymosa. J Asian Nat Prod Res. 2014;16 (4) :422-5. |[4]Shoko Taniguchi, et al. Production of bioactive triterpenes by Eriobotrya japonica calli. Phytochemistry. 2002 Feb;59 (3) :315-23.