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BPU-11

BPU-11 is a hyperpolarization-activated cyclic nucleotide-gated (HCN) C-linker pocket (CLP) HCN4 CLP ligand. BPU-11 can be used for the research of congenital immune disease[1].

Product Specifications

CAS Number

909664-41-1

Product Name Alternative

AHPN,AHPN-13C6

UNSPSC

12352005

Target

HCN Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/bpu-11.html

Concentration

10mM

Purity

98.08

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(N(CC1=CC=CN=C1)C2CCN(CC2)CC3=CC=CC(C#N)=C3)NC4=CC=CC=C4C5=CC=CC=C5

Molecular Formula

C32H31N5O

Molecular Weight

501.62

References & Citations

[1]Lolicato M, et al. Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness. Nat Chem Biol. 2014 Jun;10 (6) :457-62.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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