BPU-11
BPU-11 is a hyperpolarization-activated cyclic nucleotide-gated (HCN) C-linker pocket (CLP) HCN4 CLP ligand. BPU-11 can be used for the research of congenital immune disease[1].
Product Specifications
CAS Number
[909664-41-1]
Product Name Alternative
AHPN,AHPN-13C6
UNSPSC
12352005
Target
HCN Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bpu-11.html
Concentration
10mM
Purity
98.08
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(N(CC1=CC=CN=C1)C2CCN(CC2)CC3=CC=CC(C#N)=C3)NC4=CC=CC=C4C5=CC=CC=C5
Molecular Formula
C32H31N5O
Molecular Weight
501.62
References & Citations
[1]Lolicato M, et al. Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness. Nat Chem Biol. 2014 Jun;10 (6) :457-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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