What is the catalog number for Ac-VAD-AFC?

The catalog number for Ac-VAD-AFC is HY-P10276.

What sizes are available for Ac-VAD-AFC?

Ac-VAD-AFC is available in the following size(s): 1 Each.

Is Ac-VAD-AFC in stock?

Ac-VAD-AFC is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ac-VAD-AFC?

Ac-VAD-AFC is manufactured by QuantiMol.

What is the estimated delivery time for Ac-VAD-AFC?

Estimated delivery time for Ac-VAD-AFC is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ac-VAD-AFC?

The safety data sheet for Ac-VAD-AFC is available here: http://file.medchemexpress.com/batch_PDF/HY-P10276/.

Ac-VAD-AFC

Ac-VAD-AFC is a fluorescent substrate for caspases and can be used to test the activity of caspases[1][2].

Product Specifications

UNSPSC

12352209

Target

Caspase

Type

Peptides

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ac-vad-afc.html

Solubility

10 mM in DMSO

Smiles

O=C1OC2=C(C=C1C(F)(F)F)C=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)C(C)C)=O)C)=O)CC(O)=O)=O)=C2

Molecular Formula

C24H27F3N4O8

Molecular Weight

556.49

References & Citations

[1]Choi WS, et al. Cleavage of Bax is mediated by caspase-dependent or -independent calpain activation in dopaminergic neuronal cells: protective role of Bcl-2. J Neurochem. 2001;77 (6) :1531-1541.|[2]Posadas I, et al. Acetaminophen induces human neuroblastoma cell death through NFKB activation. PLoS One. 2012;7 (11) :e50160.