RP-54745
RP-54745 is an inhibitor of macrophage stimulation and interleukin-1 production, and a potential antirheumatic compound.
Product Specifications
CAS Number
135330-08-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/RP-54745.html
Concentration
10mM
Purity
99.79
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C1SSC(N2C(C)C3=C(C=CC=C3)CC2)=C1Cl
Molecular Formula
C13H12ClNOS2
Molecular Weight
297.82
Precautions
H302, H315, H319, H335
References & Citations
[1]Folliard F, et al. RP 54745, a potential antirheumatic compound. I. Inhibitor of macrophage stimulation and interleukin-1 production. Agents Actions. 1992 May;36 (1-2) :119-26.|[2]Folliard F, et al. RP 54745, a potential antirheumatic compound. II. In vivo properties in different animal models. Agents Actions. 1992 May;36 (1-2) :127-35.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-1
Available Sizes
Frequently Asked Questions
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