RP-54745

RP-54745 is an inhibitor of macrophage stimulation and interleukin-1 production, and a potential antirheumatic compound.

Product Specifications

CAS Number

[135330-08-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/RP-54745.html

Concentration

10mM

Purity

99.79

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=C1SSC(N2C(C)C3=C(C=CC=C3)CC2)=C1Cl

Molecular Formula

C13H12ClNOS2

Molecular Weight

297.82

Precautions

H302, H315, H319, H335

References & Citations

[1]Folliard F, et al. RP 54745, a potential antirheumatic compound. I. Inhibitor of macrophage stimulation and interleukin-1 production. Agents Actions. 1992 May;36 (1-2) :119-26.|[2]Folliard F, et al. RP 54745, a potential antirheumatic compound. II. In vivo properties in different animal models. Agents Actions. 1992 May;36 (1-2) :127-35.