FT3967385
FT3967385 is a novel USP30 inhibitor that recapitulates genetic loss of USP30 and sets the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Product Specifications
Product Name Alternative
FT385
UNSPSC
12352005
Target
Deubiquitinase; PINK1/Parkin
Type
Reference compound
Related Pathways
Autophagy; Cell Cycle/DNA Damage; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ft3967385.html
Concentration
10mM
Purity
99.74
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@H]1CN(C#N)CC1)C2=CC(C3=C(OC4=CC=CC=C4)C=CC=C3)=NN2
Molecular Formula
C21H19N5O2
Molecular Weight
373.41
References & Citations
[1]Rusilowicz-Jones E, et al. A novel USP30 inhibitor recapitulates genetic loss of USP30 and sets the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation. BioRxiv. 2020 April 20.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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