RO 4927350
RO 4927350 is a potent and selective non-ATP-competitive MEK1/2 inhibitor. RO 4927350 exhibits significant antitumor efficacy in a broad spectrum of tumor models[1].
Product Specifications
CAS Number
[876755-27-0]
UNSPSC
12352005
Target
MEK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ro-4927350.html
Smiles
C[C@@H](C1=CC=CC=C1)[C@H](N2C([C@@H](C3=CC=C(C=C3)OCCO)NC2=O)=O)C(NC4=NC(C(CC)=O)=CS4)=O
Molecular Formula
C27H28N4O6S
Molecular Weight
536.60
References & Citations
[1]Daouti S, et, al. Characterization of a novel mitogen-activated protein kinase kinase 1/2 inhibitor with a unique mechanism of action for cancer therapy. Cancer Res. 2009 Mar 1;69 (5) :1924-32.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-13303/RO-4927350-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13303/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![BTG2 Mouse Monoclonal Antibody [Clone ID: OTI4C10]](https://cdn.genprice.uk/products/937/68dd18b9061270361e90827c/imageurl/cf808197.webp)
MBS1307499-01 0.02 mg (E-Coli)
Recombinant Toxoplasma gondii Uracil phosphoribosyltransferase (uprt)
Ask
View Details MBS1307499-02 0.1 mg (E-Coli)
Recombinant Toxoplasma gondii Uracil phosphoribosyltransferase (uprt)
Ask
View Details MBS1307499-03 0.02 mg (Yeast)
Recombinant Toxoplasma gondii Uracil phosphoribosyltransferase (uprt)
Ask
View Details MBS1307499-04 0.1 mg (Yeast)
Recombinant Toxoplasma gondii Uracil phosphoribosyltransferase (uprt)
Ask
View Details 
MBS1307499-05 0.02 mg (Baculovirus)
Recombinant Toxoplasma gondii Uracil phosphoribosyltransferase (uprt)
Ask
View Details