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RO 4927350

Product Specifications

UNSPSC Description

RO 4927350 is a potent and selective non-ATP-competitive MEK1/2 inhibitor. RO 4927350 exhibits significant antitumor efficacy in a broad spectrum of tumor models[1].

Target Antigen

MEK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ro-4927350.html

Smiles

C[C@@H](C1=CC=CC=C1)[C@H](N2C([C@@H](C3=CC=C(C=C3)OCCO)NC2=O)=O)C(NC4=NC(C(CC)=O)=CS4)=O

Molecular Weight

536.60

References & Citations

[1]Daouti S, et, al. Characterization of a novel mitogen-activated protein kinase kinase 1/2 inhibitor with a unique mechanism of action for cancer therapy. Cancer Res. 2009 Mar 1;69(5):1924-32.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-13303/RO-4927350-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-13303/

Clinical Information

No Development Reported

CAS Number

876755-27-0

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