DTNP
DTNP is a BchE -activated near infrared (NIR) probe with blood-brain permeability. DTNP can be activated by BchE and inhibit its enzyme activity. DTNP can be used in Alzheimer's disease (AD) research[1].
Product Specifications
CAS Number
3010266-66-4
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dtnp.html
Solubility
10 mM in DMSO
Smiles
CC1(C(/C=C/C(CCC2)=C3C2=CC4=C(O3)C=C(OC(C5CC5)=O)C=C4)=[N+](C6=CC=CC=C61)CCCC7=CN(CCNC(C8=CC=CC(C(NC9=CC=CC(C(NCC%10=CC=CC=C%10CN(CC)CC)=O)=C9)=O)=C8)=O)N=N7)C.[I-]
Molecular Formula
C63H67IN8O6
Molecular Weight
1159.16
References & Citations
[1]Wang L, et al. Butyrylcholinesterase-Activated Near-Infrared Fluorogenic Probe for In Vivo Theranostics of Alzheimer's Disease. J Med Chem. 2024 Apr 25;67 (8) :6793-6809.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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