Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

RI (dl) -2

RI (dl) -2 blocks RAD51’s D-loop activity in biochemical systems with an IC50 value of 11.1 µM and inhibits homologous recombination (HR) activity with an IC50 value of 3.0 µM. RI (dl) -2 inhibits HR-mediated repair of DNA double strand breaks and sensitizes different cancer cell lines[1].

Product Specifications

CAS Number

1902146-75-1

UNSPSC

12352005

Target

RAD51

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ri-dl-2.html

Solubility

10 mM in DMSO

Smiles

CCNC(C=C1)=CC=C1C2=NC3=C(N4C=CC=C42)C=CC=C3

Molecular Formula

C19H17N3

Molecular Weight

287.36

References & Citations

[1]Wei Lv, et al. Development of Small Molecules that Specifically Inhibit the D-loop Activity of RAD51. J Med Chem. 2016 May 26;59 (10) :4511-25.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

TMEM100 (NM_018286) Human Over-expression Lysate
LY402665 100 µg

TMEM100 (NM_018286) Human Over-expression Lysate

Sign In for Pricing
View Details
Tissue FFPE Sections, Lung: right lower lobe
CS713871 5x 5 µm

Tissue FFPE Sections, Lung: right lower lobe

Sign In for Pricing
View Details
ARSG Mouse Monoclonal Antibody [Clone ID: OTI4H3]
CF812732 100 µg

ARSG Mouse Monoclonal Antibody [Clone ID: OTI4H3]

Sign In for Pricing
View Details
Thymidine 5’-Diphosphate Sodium Salt (~90%)
TRC-T412010-5MG 5 mg

Thymidine 5’-Diphosphate Sodium Salt (~90%)

Sign In for Pricing
View Details
Adracalin (AAAS) (NM_001173466) Human Over-expression Lysate
LY433210 100 µg

Adracalin (AAAS) (NM_001173466) Human Over-expression Lysate

Sign In for Pricing
View Details
CD14 (71-84) Goat Polyclonal Antibody
AP22502PU-N 50 µg

CD14 (71-84) Goat Polyclonal Antibody

Sign In for Pricing
View Details