HSD17B13-IN-9
HSD17B13-IN-9 (252) is a 17β-Hydroxysteroid dehydrogenases (HSD17B13) inhibitor, with an IC50 of 0.01 μM for 50 nM HSD17B13. Used in NAFLD (Nonalcoholic fatty liver diseases) research[1].
Product Specifications
CAS Number
[2576690-78-1]
UNSPSC
12352005
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hsd17b13-in-9.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC=C2C(SC3=C(C2NC(C4=CC=C(NC4=O)C(F)(F)F)=O)C=CC(C)=C3)=C1
Molecular Formula
C22H17F3N2O2S
Molecular Weight
430.44
References & Citations
[1]Joseph Vacca, et al. Modulators of hsd17b13 and methods of use thereof. Patent WO2021003295.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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