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HSD17B13-IN-9

HSD17B13-IN-9 (252) is a 17β-Hydroxysteroid dehydrogenases (HSD17B13) inhibitor, with an IC50 of 0.01 μM for 50 nM HSD17B13. Used in NAFLD (Nonalcoholic fatty liver diseases) research[1].

Product Specifications

CAS Number

2576690-78-1

UNSPSC

12352005

Target

17β-HSD

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/hsd17b13-in-9.html

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=CC=C2C(SC3=C(C2NC(C4=CC=C(NC4=O)C(F)(F)F)=O)C=CC(C)=C3)=C1

Molecular Formula

C22H17F3N2O2S

Molecular Weight

430.44

References & Citations

[1]Joseph Vacca, et al. Modulators of hsd17b13 and methods of use thereof. Patent WO2021003295.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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