Cyproterone acetate (Standard)
Cyproterone acetate (Standard) is the analytical standard of Cyproterone acetate. This product is intended for research and analytical applications. Cyproterone acetate is an anti-androgen (IC50=7.1 nM) and progestogen synthetic steroid. Cyproterone acetate has affinity with progesteron and with glucocorticoidal receptors[1][2].
Product Specifications
CAS Number
427-51-0
UNSPSC
12352211
Target
Androgen Receptor; Reference Standards
Type
Reference Standards
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Endocrinology
Assay Protocol
https://www.medchemexpress.com/cyproterone-acetate-standard.html
Smiles
C[C@@]12C(C(Cl)=C[C@]3([H])[C@]2([H])C[C@@]4(C)[C@@]3([H])CC[C@@]4(C(C)=O)OC(C)=O)=CC([C@H]5[C@@H]1C5)=O
Molecular Formula
C23H27ClO4
Molecular Weight
402.91
References & Citations
[1]Sonneveld, E., et al., Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays. Toxicol Sci, 2005. 83 (1) : p. 136-48.|[2]Torri V, . Cyproterone acetate in the therapy of prostate carcinoma. Arch Ital Urol Androl. 2005;77 (3) :157-163.|[3]Chen L, et al. Cyproterone acetate enhances TRAIL-induced androgen-independent prostate cancer cell apoptosis via up-regulation of death receptor 5. BMC Cancer. 2017;17 (1) :179. Published 2017 Mar 7.|[4]Migally N. Effect of cyproterone acetate on the structure of the adrenal cortex. Arch Androl. 1979;2 (2) :109-115.|[5]Takiguchi M, et al. Cyproterone acetate induces a cellular tolerance to cadmium in rat liver epithelial cells involving reduced cadmium accumulation. Toxicology. 2001;165 (1) :13-25.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC400226-500 1x 500 µL
Pmel17 / gp100 / SILV (NKI-beteb), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940630-100 1x 100 µL
Mucin 1 / EMA / Episialin / CD227 (VU-2G7), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC741073-500 1x 500 µL
HLA-Aw32 & HLA-A25 (MHC I) (CATA-1), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680676-500 1x 500 µL
MUC18 / Mucin 18 / CD146 (OJ79c), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC882167-100 1x 100 µL
Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details