4-Methylumbelliferyl palmitate

4-Methylumbelliferyl palmitate is an excellent fluorophore for measuring acid lipase in human leukocytes. Acidity and solvent have important influence on its fluorescence. 4-Methylumbelliferyl palmitate exists mainly as neutral molecular form which can be produced strong fluorescence at 445 nm in near neutral aqueous solutions, and exist mainly as anion form which can be produced stronger fluorescence at 445 nm in weak alkaline solutions[1][2].

Product Specifications

CAS Number

[17695-48-6]

UNSPSC

12171500

Hazard Statement

H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/4-methylumbelliferyl-palmitate.html

Purity

99.23

Solubility

DMF : 50 mg/mL (ultrasonic) |DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCCCCCCCCCCCCCCC(OC1=CC(O2)=C(C=C1)C(C)=CC2=O)=O

Molecular Formula

C26H38O4

Molecular Weight

414.59

Precautions

H315, H319, H335

References & Citations

[1]Zhi H, et al. Fluorescent properties of hymecromone and fluorimetric analysis of hymecromone in compound dantong capsule. Journal of Spectroscopy, 2013, 2013.|[2]Dairaku T, et al. Nishimura M, Endo M, Ohashi T, Eto Y. A practical fluorometric assay method to measure lysosomal acid lipase activity in dried blood spots for the screening of cholesteryl ester storage disease and Wolman disease. Mol Genet Metab. 2014 Feb;111 (2) :193-6.