E-64 (N- (N- (L-3 Trans-carboxirane-2-carbonyl) -L-leucyl) -agmatine)

<strong>E-64 (N-(N-(L-3 Trans-carboxirane-2-carbonyl)-L-leucyl)-agmatine)</strong>_x000D_ <strong>Catalog number:</strong> B2016411_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 357.4 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> (2S-(2-alpha,3-beta(R*)))-3-(((1-(((4-((aminoiminomethyl)amino)carbonyl)-3- methylbutyl)amino)carbonyl)-oxiranecarboxylicacid / E 64 / E 64 (proteinase inhibitor) / E-64 / L-trans-3-carboxyoxiran-2-carbonyl-L-leucylagmatine_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Yamamoto D, Ohishi H, Ishida T, Inoue M, Sumiya S, Kitamura K. Molecular dynamics simulation of papain-E-64 (N-[N-(L-3-trans-carboxyoxirane-2-carbonyl)-L-leucyl]agmatine) complex Chem Pharm Bull (Tokyo). 1990 Sep;38(9):2339-43._x000D_ 2: Beers EP, Freeman TB. Proteinase Activity during Tracheary Element Differentiation in Zinnia Mesophyll Cultures Plant Physiol. 1997 Mar;113(3):873-880._x000D_ 3: Alcalá-Canto Y, Ibarra-Velarde F, Sumano-Lopez H, Gracia-Mora J, Alberti-Navarro A. Dose-response inhibition of proteolytic activity by a cysteine protease inhibitor in a murine model of fasciolosis Parasitol Res. 2006 Apr;98(5):438-42._x000D_ 4: Wilson KA, Tan-Wilson A. Proteases catalyzing vicilin cleavage in developing pea (Pisum sativum L.) seeds J Plant Physiol. 2018 May-Jun;224-225:86-94._x000D_ 5: Kominami E, Hashida S, Katunuma N. Inhibitions of degradation of rat liver aldolase and lactic dehydrogenase by N-[N-(L-3-trans-carboxyoxirane-2-carbonyl)-L-leucyl] agmatine or leupeptin in vivo Biochem Biophys Res Commun. 1980 Apr 14;93(3):713-9._x000D_ 6: Alcalá-Canto Y, Ibarra-Velarde F, Gracia-Mora J, Sumano-López H. Fasciola hepatica proteolytic activity in liver revealed by in situ zymography Parasitol Res. 2005 Jul;96(5):308-11._x000D_ 7: Sueyoshi T, Hara A, Shimada T, Kimura M, Morita T, Kato H, Iwanaga S. Molecular interaction of bovine kininogen and its derivatives with papain J Biochem. 1988 Aug;104(2):200-6._x000D_ 8: Kansal RG, Nizet V, Jeng A, Chuang WJ, Kotb M. Selective modulation of superantigen-induced responses by streptococcal cysteine protease J Infect Dis. 2003 Feb 1;187(3):398-407._x000D_ 9: Nakao H, Kurita Y, Tsuboi R, Takamori K, Ogawa H. Induction and inhibition of cathepsin B and hemoglobin-hydrolase activity in murine B16 melanoma by thiol protease inhibitors Comp Biochem Physiol B. 1986;85(2):435-7._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/3007444">10: Sasaki T, Kikuchi T, Fukui I, Murachi T. Inactivation of calpain I and calpain II by specificity-oriented tripeptidyl chloromethyl ketones J Biochem. 1986 Jan;99(1):173-9. </a>_x000D_ _x000D_ <strong>Products Related to E-64 (N-(N-(L-3 Trans-carboxirane-2-carbonyl)-L-leucyl)-agmatine) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>