COL4A2, Human (His)

COL4A2 protein is a key type IV collagen element that forms the main structural component of the glomerular basement membrane (GBM), forming a unique "chicken wire" network structure with laminin, proteoglycans and nestin/nesidin. . Canstatin is a cleavage product of the NC1 domain of collagen α 2(IV) and has potent anti-angiogenic and anti-tumor activities. COL4A2 Protein, Human (His) is the recombinant human-derived COL4A2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of COL4A2 Protein, Human (His) is 220 a.a., with molecular weight of ~28.3 kDa.

VKHSQTDQEP MCPVGMNKLW SGYSLLYFEG QEKAHNQDLG LAGSCLARFS TMPFLYCNPG DVCYYASRND KSYWLSTTAP LPMMPVAEDE IKPYISRCSV CEAPAIAIAV HSQDVSIPHC PAGWRSLWIG YSFLMHTAAG DEGGGQSLVS PGSCLEDFRA TPFIECNGGR GTCHYYANKY SFWLTTIPEQ SFQGSPSADT LKAGLIRTHI SRCQVCMKNL