Deoxycholic acid (Standard)

Deoxycholic acid (Standard) is the analytical standard of Deoxycholic acid. This product is intended for research and analytical applications. Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5[1][2].

Product Specifications

CAS Number

[83-44-3]

Product Name Alternative

Cholanoic Acid (Standard) ; Desoxycholic acid (Standard)

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; G protein-coupled Bile Acid Receptor 1; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/deoxycholic-acid-standard.html

Purity

99.85

Solubility

DMSO : ≥ 100 mg/mL

Smiles

C[C@@]1([C@@]2([H])[C@H](C)CCC(O)=O)[C@](CC2)([H])[C@@](CC[C@@]3([H])[C@@]4(CC[C@@H](O)C3)C)([H])[C@]4([H])C[C@@H]1O

Molecular Formula

C24H40O4

Molecular Weight

392.57

Precautions

H302, H315, H319, H335

References & Citations

[1]Somm E, et al. β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue. JCI Insight. 2017 Apr 20;2 (8) . pii: 91809.|[2]Wang X, et al. Acidified bile acids enhance tumor progression and telomerase activity of gastric cancer in micedependent on c-Myc expression. Cancer Med. 2017 Apr;6 (4) :788-797.