OSK-1
OSK-1 is a potent Kv channel blocker with IC50s of of 0.6 nM, 5.4 nM, 0.014 nM for Kv1.1, Kv1.2 and Kv1.3, respectively. OSK1 is a moderate blocker of Ca2+-activated KCa3.1 channel with an IC50 of 225 nM. OSK-1 belongs to α-KTx3 toxins and is used as a immunosuppressive agent[1].
Product Specifications
CAS Number
183815-75-0
UNSPSC
12352209
Target
Potassium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/osk-1.html
Solubility
H2O
Smiles
O=C1NC(CCCCCC(C2OC2)O)C(NC(C)(C)C(NC(CC3=CC=CC=C3)C(N4CCCC14)=O)=O)=O
Molecular Formula
C177H300N56O46S8
Molecular Weight
4205.17
References & Citations
+
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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