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HDAC6-IN-46

HDAC6-IN-46 (compound 12) is a selective histone deacetylase 6 (HDAC6) inhibitor with an IC50 value of 6.2 nM. HDAC6-IN-46 can be used in Alzheimer's disease research[1].

Product Specifications

CAS Number

3038789-39-5

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hdac6-in-46.html

Purity

98.51

Smiles

O=C(C1=CC=C(C=C1)CN2C3=CC=CC=C3C4=C2C5OC6=C(C(N5CC4)=O)C=CC=C6)NO

Molecular Formula

C26H21N3O4

Molecular Weight

439.46

References & Citations

[1]Li SY, et al. Design, synthesis and biological activity of oxyevodiamine-based histone deacetylase 6 inhibitors. J Asian Nat Prod Res. 2024 Jun 30:1-11.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC6

Available Sizes

Frequently Asked Questions

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