Halofantrine (hydrochloride) (Standard)

Halofantrine (hydrochloride) (Standard) is the analytical standard of Halofantrine (hydrochloride) . This product is intended for research and analytical applications. Halofantrine hydrochloride (SKF-102886) is a blocker of delayed rectifier potassium current via the inhibition of human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial compound[1][2].

Product Specifications

CAS Number

[36167-63-2]

Product Name Alternative

SKF-102886 (Standard) ; WR-171669 (hydrochloride) (Standard)

UNSPSC

12352005

Target

Parasite; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/halofantrine-hydrochloride-standard.html

Smiles

OC(CCN(CCCC)CCCC)C1=CC2=C(Cl)C=C(Cl)C=C2C3=CC(C(F)(F)F)=CC=C31.[H]Cl

Molecular Formula

C26H31Cl3F3NO

Molecular Weight

536.88

References & Citations

[1]Krishna S, et al. Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria. Br J Clin Pharmacol. 1993 Dec;36 (6) :585-91.|[2]Tie, H., et al., Inhibition of HERG potassium channels by the antimalarial agent halofantrine. Br. J. Pharmacol. 130, 1967-1975, (2000) Traebert.