Skyrin

Skyrin is an anthraquinone compound that can be isolated from almond fruit. Skyrin is a receptor-selective glucagon antagonist. Skyrin can inhibit the growth of tumor cells[1][2].

Product Specifications

CAS Number

[602-06-2]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

GCGR

Type

Natural Products

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/skyrin.html

Purity

97.0

Solubility

10 mM in DMSO

Smiles

CC1=CC(O)=C2C(C(C3=C(C2=O)C(O)=CC(O)=C3C4=C(C=C(C(C(C5=C6C=C(C=C5O)C)=O)=C4C6=O)O)O)=O)=C1

Molecular Formula

C30H18O10

Molecular Weight

538.46

Precautions

H315, H319

References & Citations

[1]Parker JC, et al. Effects of skyrin, a receptor-selective glucagon antagonist, in rat and human hepatocytes. Diabetes. 2000 Dec;49 (12) :2079-86.|[2]Lin LC, et al. Cytotoxic principles from Ventilago leiocarpa. J Nat Prod. 2001 May;64 (5) :674-6.