Histone H3 (1-25), amide

Histone H3 (1-25), amide is an N-terminal peptide fragment of histone H3. Histone H3 (1-25), amide can be used to identify the substrate for histone methyltransferases (HMTs) . Histone H3 (1-25), amide, as a substrate for HMT G9a, shows more efficient than histone H3 (15-39) and full-length histone H3[1].

Product Specifications

CAS Number

[1373320-65-0]

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/histone-h3-1-25-amide.html

Solubility

10 mM in DMSO

Smiles

NC([C@H](C)NC([C@H](C)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H]1N(CCC1)C([C@H](C)NC([C@H](CCCCN)NC(CNC(CNC([C@H]([C@H](O)C)NC([C@H](CO)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H]([C@H](O)C)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@@H](NC([C@@H](N)C)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C110H202N42O32

Molecular Weight

2625.10

References & Citations

[1]Kumar M, et al. Biochemical Assay Development for Histone Methyltransferases Using a Transcreener-Based Assay for S-Adenosylhomocysteine. Assay Drug Dev Technol. 2015;13 (4) :200-209.