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DBCO-C3-amide-PEG6-NHS ester

DBCO-C3-amide-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-C3-amide-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1].

Product Specifications

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dbco-c3-amide-peg6-nhs-ester.html

Purity

95.20

Smiles

O=C(CCCC(NCCOCCOCCOCCOCCOCCOCCC(ON(C1=O)C(CC1)=O)=O)=O)N2CC(C=CC=C3)=C3C#CC4=C2C=CC=C4

Molecular Formula

C39H49N3O12

Molecular Weight

751.82

References & Citations

[1]Zimmerman ES, et al. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system. Bioconjug Chem. 2014 Feb 19;25 (2) :351-61.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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