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22-Thiocyanatosalvinorin A

22-Thiocyanatosalvinorin A (RB-64) is a potent and selective kappa-opioid receptor agonist with an EC50 of 0.077 nM[1].

Product Specifications

CAS Number

1174223-49-4

Product Name Alternative

RB-64

UNSPSC

12352211

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/22-thiocyanatosalvinorin-a.html

Smiles

C[C@@]12[C@]3([H])[C@]([C@@H](C[C@@H](C3=O)OC(CSC#N)=O)C(OC)=O)(CC[C@@]1([H])C(O[C@H](C4=COC=C4)C2)=O)C

Molecular Formula

C24H27NO8S

Molecular Weight

489.54

References & Citations

[1]Yan F, et al. Structure-based design, synthesis, and biochemical and pharmacological characterization of novel salvinorin A analogues as active state probes of the kappa-opioid receptor. Biochemistry. 2009 Jul 28;48 (29) :6898-908.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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