Levcromakalim
Levcromakalim ((-) -Cromakalim) is an ATP-sensitive K+ channel (KATP) activator.
Product Specifications
CAS Number
94535-50-9
Product Name Alternative
(-) -Cromakalim; BRL 38227
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Levcromakalim.html
Purity
99.83
Solubility
DMSO : ≥ 50 mg/mL
Smiles
CC(O1)(C)[C@@H](O)[C@H](N2CCCC2=O)C3=C1C=CC(C#N)=C3
Molecular Formula
C16H18N2O3
Molecular Weight
286.33
References & Citations
[1]Matsumoto T, et al. Tunicamycin-Induced Alterations in the Vasorelaxant Response in Organ-Cultured Superior Mesenteric Arteries of Rats. Biol Pharm Bull. 2016;39 (9) :1475-81.|[2]Hong SH, et al. Regulation of myometrial contraction by ATP-sensitive potassium (KATP) channel via activation of SUR2B and Kir 6.2 in mouse. J Vet Med Sci. 2016 Aug 1;78 (7) :1153-9.|[3]Whidden MA, Altered potassium ATP channel signaling in mesenteric arteries of old high salt-fed rats. J Exerc Nutrition Biochem. 2016 Jun;20 (2) :58-64.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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