Levcromakalim

Levcromakalim ((-) -Cromakalim) is an ATP-sensitive K+ channel (KATP) activator.

Product Specifications

CAS Number

[94535-50-9]

Product Name Alternative

(-) -Cromakalim; BRL 38227

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Levcromakalim.html

Purity

99.83

Solubility

DMSO : ≥ 50 mg/mL

Smiles

CC(O1)(C)[C@@H](O)[C@H](N2CCCC2=O)C3=C1C=CC(C#N)=C3

Molecular Formula

C16H18N2O3

Molecular Weight

286.33

References & Citations

[1]Matsumoto T, et al. Tunicamycin-Induced Alterations in the Vasorelaxant Response in Organ-Cultured Superior Mesenteric Arteries of Rats. Biol Pharm Bull. 2016;39 (9) :1475-81.|[2]Hong SH, et al. Regulation of myometrial contraction by ATP-sensitive potassium (KATP) channel via activation of SUR2B and Kir 6.2 in mouse. J Vet Med Sci. 2016 Aug 1;78 (7) :1153-9.|[3]Whidden MA, Altered potassium ATP channel signaling in mesenteric arteries of old high salt-fed rats. J Exerc Nutrition Biochem. 2016 Jun;20 (2) :58-64.