N-ε-propargyloxycarbonyl-L-lysine (hydrochloride)

N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys (Poc) -OH) hydrochloride is a lysine-based unnatural amino acid (UAA) . N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals[1][2]. N-ε-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[1428330-91-9]

Product Name Alternative

H-L-Lys (Poc) -OH (hydrochloride)

UNSPSC

12352211

Hazard Statement

H315, H319

Target

Amino Acid Derivatives

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-epsilon-propargyloxycarbonyl-l-lysine-hydrochloride.html

Concentration

10mM

Purity

99.80

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

C#CCOC(NCCCC[C@H](N)C(O)=O)=O.Cl

Molecular Formula

C10H17ClN2O4

Molecular Weight

264.71

Precautions

H315, H319

References & Citations

[1]Enke HEIKE, et al. Modified microcystins and nodularins.WO2018206715A2|[2]Kyung Jin Lee, et al. Site-Specific Labeling of Proteins Using Unnatural Amino Acids. Mol Cells. 2019 May 31;42 (5) :386-396.