H-Phe (3,5-DiF) -OH

H-Phe (3,5-DiF) -OH is a difluorophenylalanines in the L-configuration [L- (F2) Phe]. H-Phe (3,5-DiF) -OH can be incorporated into the thrombin receptor-tethered ligand peptide SFLLRNP to identify the phenyl hydrogens of the Phe-2 residue involved in the CH/π receptor interaction[1].

Product Specifications

CAS Number

[31105-91-6]

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Protease Activated Receptor (PAR)

Type

Peptides

Related Pathways

GPCR/G Protein

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/h-phe-3-5-dif-oh.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

N[C@@H](CC1=CC(F)=CC(F)=C1)C(O)=O

Molecular Formula

C9H9F2NO2

Molecular Weight

201.17

Precautions

H302, H315, H319, H335

References & Citations

[1]Fujita T, et al. Synthesis of a complete set of l-difluorophenylalanines, l- (F2) Phe, as molecular explorers for the CH/π interaction between peptide ligand and receptor. Tetrahedron Letters. 2000, 41 (6) :923-927.